Istituti Fisioterapici Ospitalieri – Istituto Nazionale Tumori Regina

Istituti Fisioterapici Ospitalieri – Istituto Nazionale Tumori Regina Elena IRCCS is a public, no profit Institution established in 04/08/1932, a center of excellence for cancer research, prevention and personalized treatment, recognized as a Scientific Research and Treatment Institute since 1939 by Italian Ministry of Health, relating to the discipline of Oncology. It bases its mission on the development of new methods of cancer prevention, diagnosis and treatment through basic, preclinical, clinical and translational research.

Role of institution in the project

The IFO-IRE is involved in Work Package 5, Tasks 5.3, on Data Anonymisation and 5.5 on Image Data FAIRification. Specifically, Data Anonymization algorithms will be tested and validated on internal imaging casuistries, while FAIRification will be evaluated on internal casuistries and disseminated to the Italian Biobank and Digital Pathology community. 

Matteo Pallocca

Matteo Pallocca graduated in Computer Science in 2013 from Sapienza University in Rome, after working for an internship for the Hubrecht Group in the Netherlands, with a thesis on lossy compression of NGS data. He was a fellow for one year in the High-Performance Computing Italian consortia CINECA building analytical pipelines for ChIP-seq, WES and RNA-seq data. From 2014 he has been working at Regina Elena National Cancer Institute, where he is coordinating the Bioinformatics group since 2017. He leads a working group on clinical reporting for Alleanza Contro il Cancro, the Italian Research Oncology Network, and taught Bioinformatics courses for Sapienza University in 2018-2020. His main research interests are results reproducibility, biomarker discovery and validation from -omics data, especially Immuno-Informatics approaches for bulk RNA-seq data reduction. From 2021 he started supporting the Clinical Informatics infrastructure at IFO-IRE, building the local Data Warehouse and connected the first Italian Biobank to the BBMRI-ERIC Federated Search Platform for the ADOPT Horizon Project.

Enzo Gallo

Enzo Gallo has expertise in digital pathology in the creation and archiving of digital slides using dedicated scanners. He is experienced in analyzing e-slides using dedicated AI software to evaluate morphological or immunohistochemical slides for different biomarkers. In addition, his research focuses on the analysis of genetic mutations in solid tumor and liquid biopsy specimens. He is also involved in the analysis of gene mutations by direct sequencing, real-time PCR and NGS sequencing on solid tumors or liquid biopsy samples. He performs data analysis using bioinformatics software and is involved in several oncology research projects investigating novel prognostic factors of interest in solid tumors, especially lung cancer, melanoma and gastric cancer.

Dr. Simona di Martino

Dr. Simona di Martino earned a Degree in Biological Science, Rome in October 2006 and obtained a PhD degree (International PhD program on “Stem Cells”) at the Italian National Institute of Health (ISS), Rome, Italy and at University of Catania, Catania, Italy. In December 2022 Simona di Martino accomplished specialization in Clinical Pathology Her field of study for different years has been genetic, molecular biology , cellular biology and biobanking. Dr Simona di Martino has gained great expertise in the processing, set-up and handling of primary tumor specimens and setting up primary cultures from established from solid tumors. At IFO-IRE Biobank, she is responsible for the organizational aspects of the tumor tissue Biobank and with her expertise coordinates and manages the activities of the BBIRE-Tissue executive group; the certification / quality / accreditation processes, defines the operating procedures and the quality control methods and takes care of the institutional interface of BBIRE-T with partners.

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